| Administrative Service |
| Bureau of Health Devices and Technology |
| Bureau of Health Facilities and Services |
| Bureau of International Health Cooperation |
| Bureau of Local Health Development |
| Bureau of Quarantine and International Health Surveillance |
| Finance Service |
| Food and Drug Administration |
| Health Emergency Management Staff |
| Health Human Resources Development Bureau |
| Health Policy Development and Planning Bureau |
| Information Management Service |
| Integrity Development Committee |
| Internal Audit Service |
| Legal Service |
| National Center for Health Facilities Development |
| National Center for Disease Prevention and Control |
| National Center for Pharmaceutical Access and Management |
| National Center for Health Promotion |
| National Epidemiology Center |
| Office of the Secretary |
| Philippine Blood Center |
| Procurement Division/COBAC Secretariat |
| Special Concerns Technical Cluster |