The functions and operations of the DOH was directed to become consistent with the provisions of Administrative Code 1987 and RA 7160 through Executive Order 102. The Health Sector Reform Agenda of the Philippines, 1999-2004 was launched.

Full implementation of Republic Act No. 7160 or Local Government Code. The DOH changed its role from one of implementation to one of governance. Significant change: branching out of the Office of the Public Health Services to form the Office for Special Concerns. Two big offices merged to become the Office of Hospital Facilities, Standards and Regulation.

Another re-organization under Executive Order No. 119, which placed under the Secretary of Health five offices headed by an undersecretary and an assistant secretary. These offices are the Chief of Staff, Public Health Services, Hospital and Facilities Services, Standard and Regulations, and Management Service.

The Ministry of Health became Department of Health again.

Under Executive Order No. 851, the Health Education and Manpower Development Service was created, and the Bureau of Food and Drugs assumed the functions of the Food and Drug Administration.

Through Letter of Implementation No. 8, pursuant to Presidential Decree No.1, Sept.24, 1972, the DOH was renamed Ministry of Health. The National Cancer Center and Radiation Health Service were created. The Ministry was divided into 12 regions covering several provinces and cities under a regional health director. Attached offices were the Philippine Medical Care Commission, the Dangerous Drugs Board, National Nutrition Council, Population Commission, National Schistosomiasis Control Council and the Tondo General Hospital.

The creation of eight regional health offices and two Undersecretaries of Health: the Undersecretary of health and the Medical Services and the Undersecretary of Special Services.
1971 The creation of the Food and Drug Administration, Bureau of Disease Intelligence Center, Malaria Eradication Service, Bureau of Dental Health Service, the National Comprehensive Maternal and Child Health / Family Planning Program, National Nutrition Program, and the National Schistosomiasis Control Commission, among others.